Author: paalgunnestad

Fig. 4. Hormone signaling. Interaction diagram of the physiological processes regarding the action of E2 and P4 on glucose metabolism (focused on insulin secretion in β-cells, glucose uptake in body tissues, and glucose storage in the liver). The left side shows the feedback loop from the HPO axis, with the Anti-Müllerian Hormone (AMH), E2 and P4 produced in and secreted by the ovaries, the Gonadotropin-releasing hormone (GnRH) by the hypothalamus and the Follicle-Stimulating Hormone (FSH) together with the Luteinizing Hormone (LH) produced in and secreted by the Pituitary. The right side is explained in Fig. 3. Pointing arrows are promoting effects, and flat-ended lines represent inhibitory effects.

New paper: How do hormonal changes during the menstrual cycle affect glucose regulation?

A new study by Carolina Ramírez Mazo, Lina Gómez-Echavarría, Laura Lema-Pérez, and Susanna Röblitz presents the first mathematical model to describe how hormonal fluctuations during the menstrual cycle influence glucose-insulin dynamics. The model integrates the effects of estradiol and progesterone on insulin sensitivity, insulin secretion, and β-cell maintenance, providing new insights into the complex interactions …

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New study highlights the role of blood proteins in communication between tissues in heart disease

Using data from the STARNET study, CBU’s Sean Bankier and the team examined the impact of plasma protein variation on gene expression in cardiometabolically relevant tissues, including liver, adipose tissue, blood, skeletal muscle, and the arterial wall. One of the key findings of this study was that plasma proteins were found to be strongly linked …

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ELIXIR at Arendalsuka 2026

ELIXIR Norway takes part in Arendalsuka 2026 with two panel debates on the future of health and research data infrastructure: one on Europe’s coordination of genomic and health data sharing, and one on federated systems as a way to share results without sharing the underlying data. Event 1: Tuesday 11 August @ 11:00 – 11:45 …

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Nathalie Reuter Elected to Prestigious Membership

Yesterday, it was announced that CBU Director Nathalie Reuter has been elected as one of the new members of EMBO! The European Molecular Biology Organization (EMBO) is an organization that grants membership to outstanding researchers in the life sciences. Only 13 Norwegian researchers have previously received this distinction. Congratulations and well deserved! Full story here

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New Study Reveals How Key Immune Regulator Shapes Interferon Signals in Developing T Cells

A new study shows that the Aire protein—best known for helping the immune system learn to tolerate the body’s own tissues—also plays an important role in producing interferons within the thymus. Using single‑cell RNA sequencing, researchers found that mice lacking Aire had weakened interferon‑driven signals in several developing thymus cell types, including maturing T cells …

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