In a new study published in Nature, researchers from the University of Geneva, the EMBL and CBU/UiB present the first large-scale map of the lipids processed by lipid transfer proteins (LTPs) in human cells.  The study identified nearly 500 new LTP-ligands pairs, including both well-studied LTPs and those that were formerly orphaned. Nathalie Reuter and her group used molecular models and simulations to examine the protein-lipid pairs identified experimentally and explain the lipid specificity for several of them.

Reza Talandashti, Florian Echelard and Mahmoud Moqadam all had decisive contributions to the work, which was conducted at the Department of Chemistry and at the Computational Biology Unit. At UiB the project was funded by the Norwegian Research Council (#288008) and benefitted from computational resources from the national infrastructure at Sigma2.

Here is a link to the study

Here you can read UiB’s news article in English and

here in Norwegian